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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA PRKCB CTRPv2 pan-cancer AAC -0.12 0.005
mRNA IQGAP1 GDSC1000 pan-cancer AAC -0.092 0.005
mRNA MFSD12 GDSC1000 pan-cancer AAC -0.11 0.005
mRNA ZNF623 GDSC1000 pan-cancer AAC 0.087 0.005
mRNA ZCCHC2 GDSC1000 pan-cancer AAC 0.089 0.005
mRNA HSPB8 GDSC1000 pan-cancer AAC -0.1 0.005
mRNA WNT3 GDSC1000 pan-cancer AAC -0.09 0.005
mRNA ERCC4 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA OR8K1 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA AVPI1 GDSC1000 pan-cancer AAC -0.11 0.005
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