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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA PRKAR2A GDSC1000 pan-cancer AAC -0.087 0.005
mRNA ATAD2 GDSC1000 pan-cancer AAC 0.09 0.005
mRNA UAP1 GDSC1000 pan-cancer AAC -0.09 0.005
mRNA AGAP2 GDSC1000 pan-cancer AAC 0.11 0.005
mRNA SMARCC1 GDSC1000 pan-cancer AAC 0.096 0.005
mRNA GFI1B CTRPv2 pan-cancer AAC -0.1 0.005
mRNA TGDS CTRPv2 pan-cancer AAC -0.12 0.005
mRNA MTM1 GDSC1000 pan-cancer AAC 0.096 0.005
mRNA CT45A10 GDSC1000 pan-cancer AAC -0.086 0.005
mRNA SMARCA5 GDSC1000 pan-cancer AAC 0.096 0.005
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