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ZSTK474

ZSTK474

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	ZSTK474
PharmacoGx	ZSTK474

External IDs

Database	Identifier
Smiles:	FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem:	11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ZSTK474

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SMO	GDSC1000	pan-cancer	AAC	0.096	0.005
mRNA	ZNF7	GDSC1000	pan-cancer	AAC	0.086	0.005
mRNA	CNOT8	GDSC1000	pan-cancer	AAC	0.091	0.005
mRNA	C1orf54	CTRPv2	pan-cancer	AAC	0.11	0.005
mRNA	RP4-614O4.11	CTRPv2	pan-cancer	AAC	-0.11	0.005
mRNA	ZFP30	GDSC1000	pan-cancer	AAC	0.091	0.005
mRNA	EP300	GDSC1000	pan-cancer	AAC	0.09	0.005
mRNA	GOLGA8S	CTRPv2	pan-cancer	AAC	0.1	0.005
mRNA	FAM78B	GDSC1000	pan-cancer	AAC	-0.096	0.005
mRNA	NIT2	CTRPv2	pan-cancer	AAC	0.11	0.005

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