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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA CRYBB2 CTRPv2 pan-cancer AAC -0.1 0.004
mRNA ITGB2 GDSC1000 pan-cancer AAC 0.1 0.004
mRNA MRPS18B CTRPv2 pan-cancer AAC -0.11 0.004
mRNA RP13-512J5.1 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA DDX6 GDSC1000 pan-cancer AAC 0.089 0.004
mRNA BCAP29 GDSC1000 pan-cancer AAC -0.091 0.004
mRNA SLC25A37 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA FLT3 GDSC1000 pan-cancer AAC 0.091 0.004
mRNA RP11-343C2.11 CTRPv2 pan-cancer AAC -0.1 0.004
mRNA SF3A2 GDSC1000 pan-cancer AAC 0.094 0.004
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