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ZSTK474

ZSTK474

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	ZSTK474
PharmacoGx	ZSTK474

External IDs

Database	Identifier
Smiles:	FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem:	11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to ZSTK474

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NDEL1	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	EPHB1	GDSC1000	pan-cancer	AAC	-0.087	0.004
mRNA	ADAMTSL5	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	TIMELESS	GDSC1000	pan-cancer	AAC	0.092	0.004
mRNA	NABP1	GDSC1000	pan-cancer	AAC	-0.094	0.004
mRNA	BAHCC1	GDSC1000	pan-cancer	AAC	0.089	0.004
mRNA	FNBP4	GDSC1000	pan-cancer	AAC	0.094	0.004
mRNA	HNRNPA2B1	GDSC1000	pan-cancer	AAC	0.088	0.004
mRNA	CCNG2	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	BORCS8-MEF2B	CTRPv2	pan-cancer	AAC	0.11	0.004

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