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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA MYH4 CTRPv2 pan-cancer AAC -0.1 0.004
mRNA GAK GDSC1000 pan-cancer AAC 0.092 0.004
mRNA SMCO4 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA CD151 GDSC1000 pan-cancer AAC -0.11 0.004
mRNA LY6G6F CTRPv2 pan-cancer AAC -0.11 0.004
mRNA SENP3-EIF4A1 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA EMP1 GDSC1000 pan-cancer AAC -0.1 0.004
mRNA GIMAP8 GDSC1000 pan-cancer AAC 0.091 0.004
mRNA SNX9 GDSC1000 pan-cancer AAC -0.12 0.004
mRNA VAV1 GDSC1000 pan-cancer AAC 0.13 0.004
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