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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA FAM210A GDSC1000 pan-cancer AAC -0.096 0.004
mRNA GYPA CTRPv2 pan-cancer AAC -0.1 0.004
mRNA FAM129B GDSC1000 pan-cancer AAC -0.14 0.004
mRNA ADAMTS2 GDSC1000 pan-cancer AAC -0.09 0.004
mRNA RBM15B GDSC1000 pan-cancer AAC 0.09 0.004
mRNA MRPS35 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA SPDYC CTRPv2 pan-cancer AAC -0.1 0.004
mRNA CEP97 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA VANGL2 GDSC1000 pan-cancer AAC 0.094 0.004
mRNA PTOV1 CTRPv2 pan-cancer AAC 0.11 0.004
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