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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA IFNLR1 CTRPv2 pan-cancer AAC 0.16 3e-05
mRNA RCOR3 CTRPv2 pan-cancer AAC 0.16 3e-05
mRNA STAT5A CTRPv2 pan-cancer AAC -0.17 3e-05
mRNA EXT2 GDSC1000 pan-cancer AAC -0.15 3e-05
mRNA ETS2 CTRPv2 pan-cancer AAC -0.16 3e-05
mRNA N4BP3 GDSC1000 pan-cancer AAC 0.14 3e-05
mRNA CDK13 CTRPv2 pan-cancer AAC 0.15 3e-05
mRNA ARHGAP30 CTRPv2 pan-cancer AAC 0.24 4e-05
mRNA CAPN2 GDSC1000 pan-cancer AAC -0.17 4e-05
mRNA RAG2 GDSC1000 pan-cancer AAC 0.13 4e-05
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