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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA E2F2 CTRPv2 pan-cancer AAC 0.18 3e-05
mRNA BLNK GDSC1000 pan-cancer AAC 0.15 3e-05
mRNA SEC11A GDSC1000 pan-cancer AAC -0.13 3e-05
mRNA DRAXIN CTRPv2 pan-cancer AAC 0.15 3e-05
mRNA IGF2BP2 CTRPv2 pan-cancer AAC -0.17 3e-05
mRNA NFATC4 CTRPv2 pan-cancer AAC 0.16 3e-05
mRNA RP11-212D19.4 CTRPv2 pan-cancer AAC -0.16 3e-05
mRNA CCDC117 CTRPv2 pan-cancer AAC 0.16 3e-05
mRNA GADD45A GDSC1000 pan-cancer AAC -0.13 3e-05
mRNA ARPP21 GDSC1000 pan-cancer AAC 0.13 3e-05
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