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ZSTK474

Synonyms

SourcesNames Used
GDSC1000, CTRPv2ZSTK474
PharmacoGx ZSTK474

External IDs

DatabaseIdentifier
Smiles: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
Pubchem: 11647372

Annotated Targets

PIK3CD, PIK3CB, PIK3CG

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZSTK474


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS35 GDSC1000 pan-cancer AAC 0.14 4e-05
mRNA ARL11 GDSC1000 pan-cancer AAC 0.15 5e-05
mRNA EVA1A GDSC1000 pan-cancer AAC -0.15 5e-05
mRNA TOPORS GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA MYADML2 CTRPv2 pan-cancer AAC 0.15 5e-05
mRNA RBMX GDSC1000 pan-cancer AAC 0.14 5e-05
mRNA UGGT2 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA RP11-345F18.1 CTRPv2 pan-cancer AAC -0.15 5e-05
mRNA ZNF136 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA EXOC3L2 CTRPv2 pan-cancer AAC -0.15 5e-05
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