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canertinib

canertinib

Synonyms

Sources	Names Used
CTRPv2	canertinib
PharmacoGx	canertinib

External IDs

Database	Identifier
Smiles:	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl
Pubchem:	156414

Annotated Targets

ERBB4, EGFR, ERBB2, AKT1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to canertinib

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	OPN3	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	SMPDL3B	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	CLDN7	CTRPv2	pan-cancer	AAC	0.17	0.0001
mRNA	ICK	CTRPv2	pan-cancer	AAC	-0.15	0.0001
mRNA	RARG	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	MLLT6	CTRPv2	pan-cancer	AAC	0.15	0.0001
mRNA	C4orf19	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	FAM216A	CTRPv2	pan-cancer	AAC	-0.16	0.0001
mRNA	G6PC3	CTRPv2	pan-cancer	AAC	-0.15	0.0001
mRNA	POLR3GL	CTRPv2	pan-cancer	AAC	-0.15	0.0001

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