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linifanib

Synonyms

SourcesNames Used
GDSC1000Linifanib
CTRPv2linifanib
PharmacoGx linifanib

External IDs

DatabaseIdentifier
Smiles: Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1
Pubchem: 11485656

Annotated Targets

CSF1R, CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRB, RET, TEK

FDA Approval Status

Not Approved
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Top molecular features associated with response to linifanib


Feature TypeStandardized
Nominal ANOVA
mRNA HHEX GDSC1000 pan-cancer AAC 0.12 0.003
mRNA NSMAF CTRPv2 pan-cancer AAC 0.11 0.003
mRNA ERMP1 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA GNPAT CTRPv2 pan-cancer AAC 0.11 0.003
mRNA GCAT CTRPv2 pan-cancer AAC 0.11 0.003
mRNA RMND5B GDSC1000 pan-cancer AAC -0.1 0.003
mRNA TMEM132E CTRPv2 pan-cancer AAC 0.1 0.003
mRNA MAP10 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA COQ10B CTRPv2 pan-cancer AAC -0.11 0.003
mRNA PLA2G12A GDSC1000 pan-cancer AAC -0.11 0.003
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