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Compounds
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ML312
ML312
Synonyms
Sources
Names Used
CTRPv2
ML312
PharmacoGx
ML312
Annotated Targets
SCARB1
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with ML312
(per dataset)
0
20
40
60
80
100
120
140
160
180
200
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
214
Download SVG
Number of tissues tested with ML312 (per
dataset)
0
2
4
6
8
10
12
14
16
18
20
22
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
22
Download SVG
Dataset Select
all
CTRPv2
ML312: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
U-2-OS
U-2-OS
NCI-H2291
NCI-H2291
COLO-699
COLO-699
NCI-H1734
NCI-H1734
CAL-12T
CAL-12T
COLO-741
COLO-741
SNU-46
SNU-46
Ki-JK
Ki-JK
YD-15
YD-15
HCC1569
HCC1569
YD-38
YD-38
SNU-668
SNU-668
NCI-H292
NCI-H292
RERF-LC-Ad1
RERF-LC-Ad1
SNU-1214
SNU-1214
253J
253J
NCO2
NCO2
SNU-C2A
SNU-C2A
SNU-182
SNU-182
SNU-478
SNU-478
NCI-H1155
NCI-H1155
TTTHYROID
TTTHYROID
HuH-28
HuH-28
SNU-1272
SNU-1272
RL95-2
RL95-2
RH-41
RH-41
PF-382
PF-382
DLD-1
DLD-1
SNU-308
SNU-308
HCC-1833
HCC-1833
A375
A375
A549
A549
SNU-201
SNU-201
SUIT-2
SUIT-2
HARA
HARA
HCC-15
HCC-15
KP-4
KP-4
NCI-H358
NCI-H358
KE-37
KE-37
639-V
639-V
BxPC-3
BxPC-3
GSS
GSS
HCC-366
HCC-366
KURAMOCHI
KURAMOCHI
LS-411N
LS-411N
ONCO-DG-1
ONCO-DG-1
SK-CO-1
SK-CO-1
CFPAC-1
CFPAC-1
HT
HT
KU-19-19
KU-19-19
OVTOKO
OVTOKO
SNU-1077
SNU-1077
OS-RC-2
OS-RC-2
SBC-5
SBC-5
SNU-119
SNU-119
DOV13
DOV13
AGS
AGS
HEC-108
HEC-108
NCI-H1838
NCI-H1838
NCI-H929
NCI-H929
U-2-OS
NCI-H2291
COLO-699
NCI-H1734
CAL-12T
COLO-741
SNU-46
Ki-JK
YD-15
HCC1569
YD-38
SNU-668
NCI-H292
RERF-LC-Ad1
SNU-1214
253J
NCO2
SNU-C2A
SNU-182
SNU-478
NCI-H1155
TTTHYROID
HuH-28
SNU-1272
RL95-2
RH-41
PF-382
DLD-1
SNU-308
HCC-1833
A375
A549
SNU-201
SUIT-2
HARA
HCC-15
KP-4
NCI-H358
KE-37
639-V
BxPC-3
GSS
HCC-366
KURAMOCHI
LS-411N
ONCO-DG-1
SK-CO-1
CFPAC-1
HT
KU-19-19
OVTOKO
SNU-1077
OS-RC-2
SBC-5
SNU-119
DOV13
AGS
HEC-108
NCI-H1838
NCI-H929
U-2-OS: 0.28
Synonyms: U-2-OS, U-2 OS, U-2_OS, U2OS
NCI-H2291: 0.28
Synonyms: NCI-H2291, NCIH2291
COLO-699: 0.19
Synonyms: COLO-699, COLO 699, COLO699
NCI-H1734: 0.17
Synonyms: NCI-H1734, NCIH1734
CAL-12T: 0.14
Synonyms: CAL-12T, CAL12T
COLO-741: 0.13
Synonyms: COLO-741, COLO 741, COLO_741, COLO741
SNU-46: 0.12
Synonyms: SNU-46, SNU46
Ki-JK: 0.11
Synonyms: Ki-JK, KIJK
YD-15: 0.11
Synonyms: YD-15, YD15
HCC1569: 0.11
Synonyms: HCC1569, hcc1569
YD-38: 0.11
Synonyms: YD-38, YD38
SNU-668: 0.10
Synonyms: SNU-668, SNU668
NCI-H292: 0.10
Synonyms: NCI-H292, H292
RERF-LC-Ad1: 0.10
Synonyms: RERF-LC-Ad1, RERFLCAD1
SNU-1214: 0.09
Synonyms: SNU-1214, SNU1214
253J: 0.09
Synonyms: 253J
NCO2: 0.09
Synonyms: NCO2
SNU-C2A: 0.09
Synonyms: SNU-C2A, SNUC2A
SNU-182: 0.09
Synonyms: SNU-182, SNU182
SNU-478: 0.09
Synonyms: SNU-478, SNU478
NCI-H1155: 0.09
Synonyms: NCI-H1155, NCIH1155
TTTHYROID: 0.09
Synonyms: TTTHYROID
HuH-28: 0.08
Synonyms: HuH-28, HuH28, HUH28
SNU-1272: 0.08
Synonyms: SNU-1272, SNU1272
RL95-2: 0.07
Synonyms: RL95-2, RL952
RH-41: 0.07
Synonyms: RH-41, RH41
PF-382: 0.07
Synonyms: PF-382, PF382
DLD-1: 0.07
Synonyms: DLD-1, DLD1
SNU-308: 0.06
Synonyms: SNU-308, SNU308
HCC-1833: 0.06
Synonyms: HCC-1833, HCC1833
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
A375: 0.00
Synonyms: A375, A-375
A549: 0.00
Synonyms: A549
SNU-201: 0.00
Synonyms: SNU-201, SNU201
SUIT-2: 0.00
Synonyms: SUIT-2, SUIT2
HARA: 0.00
Synonyms: HARA
HCC-15: 0.00
Synonyms: HCC-15, HCC15
KP-4: 0.00
Synonyms: KP-4, KP4
NCI-H358: 0.00
Synonyms: NCI-H358, NCIH358
KE-37: 0.00
Synonyms: KE-37, KE37
639-V: 0.00
Synonyms: 639-V, 639V
BxPC-3: 0.00
Synonyms: BxPC-3, BXPC3
GSS: 0.00
Synonyms: GSS
HCC-366: 0.00
Synonyms: HCC-366, HCC366
KURAMOCHI: 0.00
Synonyms: KURAMOCHI
LS-411N: 0.00
Synonyms: LS-411N, LS411N
ONCO-DG-1: 0.00
Synonyms: ONCO-DG-1, ONCODG1
SK-CO-1: 0.00
Synonyms: SK-CO-1, SKCO1
CFPAC-1: 0.00
Synonyms: CFPAC-1, CFPAC1
HT: 0.00
Synonyms: HT
KU-19-19: 0.00
Synonyms: KU-19-19, KU1919
OVTOKO: 0.00
Synonyms: OVTOKO
SNU-1077: 0.00
Synonyms: SNU-1077, SNU1077
OS-RC-2: 0.00
Synonyms: OS-RC-2, OSRC2
SBC-5: 0.00
Synonyms: SBC-5, SBC5
SNU-119: 0.00
Synonyms: SNU-119, SNU119
DOV13: 0.00
Synonyms: DOV13
AGS: 0.00
Synonyms: AGS
HEC-108: 0.00
Synonyms: HEC-108, HEC108
NCI-H1838: 0.00
Synonyms: NCI-H1838, NCIH1838
NCI-H929: 0.00
Synonyms: NCI-H929, NCIH929
Download SVG
1.50
2.00
2.50
3.00
3.50
4.00
4.50
5.00
5.50
6.00
6.50
7.00
7.50
SNU-182
SNU-182
JHUEM-2
JHUEM-2
EHEB
EHEB
U-87-MG
U-87-MG
NCI-H1299
NCI-H1299
NCO2
NCO2
JURKAT
JURKAT
KMRC-20
KMRC-20
ONS-76
ONS-76
PEER
PEER
BHY
BHY
SU-DHL-1
SU-DHL-1
P31-FUJ
P31-FUJ
MOLM-13
MOLM-13
EM-2
EM-2
JVM-3
JVM-3
MHH-ES-1
MHH-ES-1
RPMI-8402
RPMI-8402
MCF7
MCF7
SNU-878
SNU-878
KMS-21BM
KMS-21BM
SNU-620
SNU-620
Hep 3B2.1-7
Hep 3B2.1-7
SF295
SF295
SNU-182
JHUEM-2
EHEB
U-87-MG
NCI-H1299
NCO2
JURKAT
KMRC-20
ONS-76
PEER
BHY
SU-DHL-1
P31-FUJ
MOLM-13
EM-2
JVM-3
MHH-ES-1
RPMI-8402
MCF7
SNU-878
KMS-21BM
SNU-620
Hep 3B2.1-7
SF295
SNU-182: 7.42 (log10 µM)
Synonyms: SNU-182, SNU182
JHUEM-2: 6.55 (log10 µM)
Synonyms: JHUEM-2, JHUEM2
EHEB: 5.00 (log10 µM)
Synonyms: EHEB
U-87-MG: 4.03 (log10 µM)
Synonyms: U-87-MG, U-87 MG, U-87_MG, U87MG
NCI-H1299: 2.50 (log10 µM)
Synonyms: NCI-H1299, NCIH1299
NCO2: 2.42 (log10 µM)
Synonyms: NCO2
JURKAT: 2.40 (log10 µM)
Synonyms: JURKAT, Jurkat
KMRC-20: 2.40 (log10 µM)
Synonyms: KMRC-20, KMRC20
ONS-76: 2.20 (log10 µM)
Synonyms: ONS-76, ONS76
PEER: 2.20 (log10 µM)
Synonyms: PEER
BHY: 2.17 (log10 µM)
Synonyms: BHY
SU-DHL-1: 2.12 (log10 µM)
Synonyms: SU-DHL-1, SUDHL1
P31-FUJ: 2.07 (log10 µM)
Synonyms: P31-FUJ, P31/FUJ, P31_FUJ, P31FUJ
MOLM-13: 2.05 (log10 µM)
Synonyms: MOLM-13, MOLM13
EM-2: 2.05 (log10 µM)
Synonyms: EM-2, EM2
JVM-3: 2.04 (log10 µM)
Synonyms: JVM-3, JVM3
MHH-ES-1: 2.03 (log10 µM)
Synonyms: MHH-ES-1, MHHES1
RPMI-8402: 2.03 (log10 µM)
Synonyms: RPMI-8402, RPMI8402
MCF7: 1.94 (log10 µM)
Synonyms: MCF7, MCF-7, mcf7
SNU-878: 1.94 (log10 µM)
Synonyms: SNU-878, SNU878
KMS-21BM: 1.92 (log10 µM)
Synonyms: KMS-21BM, KMS21BM
SNU-620: 1.89 (log10 µM)
Synonyms: SNU-620, SNU620
Hep 3B2.1-7: 1.69 (log10 µM)
Synonyms: Hep 3B2.1-7, Hep_3B2.1-7, Hep3B2-1-7, Hep 3B2_1-7, Hep_3B2_1-7, HEP3B217
SF295: 1.14 (log10 µM)
Synonyms: SF295, SF-295
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
ML312: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
ovary
ovary
urinary_tract
urinary_tract
pancreas
pancreas
endometrium
endometrium
skin
skin
central_nervous_system
central_nervous_system
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
liver
liver
kidney
kidney
stomach
stomach
large_intestine
large_intestine
oesophagus
oesophagus
thyroid
thyroid
breast
breast
lung
lung
pleura
pleura
bone
bone
upper_aerodigestive_tract
upper_aerodigestive_tract
prostate
prostate
biliary_tract
biliary_tract
soft_tissue
soft_tissue
salivary_gland
salivary_gland
0.00
0.50
1.00
1.50
2.00
2.50
3.00
3.50
4.00
4.50
5.00
5.50
pleura
pleura
soft_tissue
soft_tissue
lung
lung
stomach
stomach
liver
liver
breast
breast
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
central_nervous_system
central_nervous_system
urinary_tract
urinary_tract
biliary_tract
biliary_tract
skin
skin
kidney
kidney
thyroid
thyroid
oesophagus
oesophagus
prostate
prostate
salivary_gland
salivary_gland
bone
bone
upper_aerodigestive_tract
upper_aerodigestive_tract
large_intestine
large_intestine
ovary
ovary
pancreas
pancreas
endometrium
endometrium
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to ML312
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
TONSL
CTRPv2
pan-cancer
AAC
0.14
0.08
mRNA
MARS
CTRPv2
pan-cancer
AAC
-0.14
0.08
mRNA
AC037459.4
CTRPv2
pan-cancer
AAC
0.14
0.08
mRNA
OR2A7
CTRPv2
pan-cancer
AAC
0.14
0.08
mRNA
TMEM99
CTRPv2
pan-cancer
AAC
-0.13
0.08
mRNA
C7orf49
CTRPv2
pan-cancer
AAC
0.14
0.08
mRNA
GTF3C2
CTRPv2
pan-cancer
AAC
0.14
0.08
mRNA
TMSB15A
CTRPv2
pan-cancer
AAC
0.13
0.08
mRNA
MTERF3
CTRPv2
pan-cancer
AAC
-0.13
0.08
mRNA
TKFC
CTRPv2
pan-cancer
AAC
-0.13
0.08
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