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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	A2ML1	GDSC1000	pan-cancer	AAC	0.094	0.002
mRNA	AAAS	CTRPv2	pan-cancer	AAC	0.093	0.007
mRNA	ABCB10	GDSC1000	pan-cancer	AAC	0.13	3e-05
mRNA	ABCB11	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	ABCC2	GDSC1000	pan-cancer	AAC	-0.081	0.006
mRNA	ABHD16B	CTRPv2	pan-cancer	AAC	-0.089	0.007
mRNA	ABHD17B	GDSC1000	pan-cancer	AAC	0.11	0.0003
mRNA	ABHD18	GDSC1000	pan-cancer	AAC	0.11	0.002
mRNA	ABHD6	GDSC1000	pan-cancer	AAC	0.11	0.0006
mRNA	ABL2	CTRPv2	pan-cancer	AAC	-0.12	0.0009

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