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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GIMAP2	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	OSER1	CTRPv2	pan-cancer	AAC	-0.13	0.0001
mRNA	ILKAP	GDSC1000	pan-cancer	AAC	0.11	0.0001
mRNA	KMT2A	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	TMEM120A	GDSC1000	pan-cancer	AAC	-0.11	0.0001
mRNA	AKNA	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	ZBTB16	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	DDX5	GDSC1000	pan-cancer	AAC	0.11	0.0001
mRNA	RGMB	GDSC1000	pan-cancer	AAC	-0.12	0.0001
mRNA	HBG2	GDSC1000	pan-cancer	AAC	0.11	0.0001

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