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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF43	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	ANP32A	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	CYB5R3	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	DYNC1LI2	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	ARL5A	GDSC1000	pan-cancer	AAC	0.12	0.0001
mRNA	DOCK8	GDSC1000	pan-cancer	AAC	0.17	0.0001
mRNA	CLDN14	GDSC1000	pan-cancer	AAC	-0.11	0.0001
mRNA	ASPH	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	EVA1A	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	NACA	GDSC1000	pan-cancer	AAC	0.12	0.0001

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