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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	APELA	GDSC1000	pan-cancer	AAC	0.083	0.007
mRNA	CSTF2T	GDSC1000	pan-cancer	AAC	0.079	0.007
mRNA	HLA-DQB2	CTRPv2	pan-cancer	AAC	0.088	0.007
mRNA	PAPOLG	CTRPv2	pan-cancer	AAC	0.092	0.007
mRNA	LRRC40	GDSC1000	pan-cancer	AAC	0.082	0.007
mRNA	SAMD14	CTRPv2	pan-cancer	AAC	0.099	0.007
mRNA	MRPS26	GDSC1000	pan-cancer	AAC	0.076	0.007
mRNA	EIF4ENIF1	GDSC1000	pan-cancer	AAC	0.084	0.007
mRNA	SEC61A1	GDSC1000	pan-cancer	AAC	-0.077	0.007
mRNA	C1orf189	GDSC1000	pan-cancer	AAC	-0.076	0.007

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