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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ATXN7L3	CTRPv2	pan-cancer	AAC	0.095	0.005
mRNA	HIST1H2AE	CTRPv2	pan-cancer	AAC	-0.093	0.005
mRNA	DNAJC28	GDSC1000	pan-cancer	AAC	0.079	0.005
mRNA	OR2A2	CTRPv2	pan-cancer	AAC	-0.089	0.005
mRNA	C1S	GDSC1000	pan-cancer	AAC	-0.091	0.005
mRNA	SLC25A27	GDSC1000	pan-cancer	AAC	-0.078	0.005
mRNA	LGALS3	GDSC1000	pan-cancer	AAC	-0.094	0.005
mRNA	BID	CTRPv2	pan-cancer	AAC	0.093	0.005
mRNA	LRRC8E	CTRPv2	pan-cancer	AAC	-0.11	0.005
mRNA	PRR30	CTRPv2	pan-cancer	AAC	0.087	0.005

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