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TPCA-1

TPCA-1

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	TPCA-1
PharmacoGx	TPCA-1

External IDs

Database	Identifier
Smiles:	NC(=O)Nc1sc(cc1C(=O)N)c2ccc(F)cc2
Pubchem:	9903786

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to TPCA-1

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SPAST	CTRPv2	pan-cancer	AAC	0.093	0.007
mRNA	NFKBIA	CTRPv2	pan-cancer	AAC	0.089	0.007
mRNA	TCTN3	GDSC1000	pan-cancer	AAC	-0.078	0.007
mRNA	ZNF85	GDSC1000	pan-cancer	AAC	0.083	0.007
mRNA	ZFP36L2	CTRPv2	pan-cancer	AAC	0.094	0.007
mRNA	FNBP1	CTRPv2	pan-cancer	AAC	0.095	0.007
mRNA	CSNK2A1	GDSC1000	pan-cancer	AAC	0.076	0.007
mRNA	EVI5L	CTRPv2	pan-cancer	AAC	-0.093	0.007
mRNA	DNMT1	GDSC1000	pan-cancer	AAC	0.086	0.007
mRNA	HTATSF1	GDSC1000	pan-cancer	AAC	0.08	0.007

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