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SJ-172550

SJ-172550

Synonyms

Sources	Names Used
CTRPv2	SJ-172550
PharmacoGx	SJ-172550

External IDs

Database	Identifier
Smiles:	CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC
Inchikey:	RKKFQJXGAQWHBZ-LICLKQGHSA-N
Pubchem:	1317464

Annotated Targets

MDM4, MDM2, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SJ-172550

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	URGCP-MRPS24	CTRPv2	pan-cancer	AAC	-0.12	0.002
mRNA	HTR2B	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	CXCL2	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	TNFSF8	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	NHLRC4	CTRPv2	pan-cancer	AAC	0.13	0.002
mRNA	HMP19	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	ARID3A	CTRPv2	pan-cancer	AAC	0.13	0.002
mRNA	LINC00521	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ATG7	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	CCNDBP1	CTRPv2	pan-cancer	AAC	0.12	0.003

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