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SJ-172550

SJ-172550

Synonyms

Sources	Names Used
CTRPv2	SJ-172550
PharmacoGx	SJ-172550

External IDs

Database	Identifier
Smiles:	CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC
Inchikey:	RKKFQJXGAQWHBZ-LICLKQGHSA-N
Pubchem:	1317464

Annotated Targets

MDM4, MDM2, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SJ-172550

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	IGF2	CTRPv2	pan-cancer	AAC	0.13	0.0008
mRNA	TNFSF15	CTRPv2	pan-cancer	AAC	0.13	0.0008
mRNA	ILDR1	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	CHRNB3	CTRPv2	pan-cancer	AAC	0.12	0.0009
mRNA	DCTN4	CTRPv2	pan-cancer	AAC	0.14	0.0009
mRNA	SLC45A1	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	DOPEY1	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	ANKHD1-EIF4EBP3	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	SGK2	CTRPv2	pan-cancer	AAC	0.14	0.0009
mRNA	CACFD1	CTRPv2	pan-cancer	AAC	0.14	0.0009

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