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SJ-172550

SJ-172550

Synonyms

Sources	Names Used
CTRPv2	SJ-172550
PharmacoGx	SJ-172550

External IDs

Database	Identifier
Smiles:	CCOC1=C(C(=CC(=C1)C=C2C(=NN(C2=O)C3=CC=CC=C3)C)Cl)OCC(=O)OC
Inchikey:	RKKFQJXGAQWHBZ-LICLKQGHSA-N
Pubchem:	1317464

Annotated Targets

MDM4, MDM2, TP53

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to SJ-172550

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DYRK1B	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	VSIG1	CTRPv2	pan-cancer	AAC	0.13	0.0005
mRNA	FOXO4	CTRPv2	pan-cancer	AAC	0.14	0.0006
mRNA	RP1-138B7.6	CTRPv2	pan-cancer	AAC	0.14	0.0006
mRNA	PPP1R1B	CTRPv2	pan-cancer	AAC	0.14	0.0006
mRNA	UROS	CTRPv2	pan-cancer	AAC	0.13	0.0006
mRNA	C8A	CTRPv2	pan-cancer	AAC	0.13	0.0006
mRNA	PCDHB11	CTRPv2	pan-cancer	AAC	0.14	0.0006
mRNA	MRGBP	CTRPv2	pan-cancer	AAC	-0.13	0.0006
mRNA	FSD1L	CTRPv2	pan-cancer	AAC	0.13	0.0006

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