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neratinib

Synonyms

SourcesNames Used
CTRPv2neratinib
PharmacoGx neratinib

External IDs

DatabaseIdentifier
Smiles: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
Inchikey: JWNPDZNEKVCWMY-VQHVLOKHSA-N
Pubchem: 9915743

Annotated Targets

EGFR, ERBB2, KDR

FDA Approval Status

Approved
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Top molecular features associated with response to neratinib


Feature TypeStandardized
Nominal ANOVA
mRNA MAFB CTRPv2 pan-cancer AAC 0.086 0.02
mRNA HIPK2 CTRPv2 pan-cancer AAC -0.089 0.02
mRNA EVC CTRPv2 pan-cancer AAC -0.093 0.02
mRNA ZNF480 CTRPv2 pan-cancer AAC 0.088 0.02
mRNA CEP126 CTRPv2 pan-cancer AAC -0.087 0.02
mRNA HS6ST2 CTRPv2 pan-cancer AAC 0.088 0.02
mRNA HGH1 CTRPv2 pan-cancer AAC 0.088 0.02
mRNA TBX18 CTRPv2 pan-cancer AAC -0.089 0.02
mRNA STC2 CTRPv2 pan-cancer AAC -0.087 0.02
mRNA ELOVL7 CTRPv2 pan-cancer AAC 0.094 0.02
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