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neratinib

Synonyms

SourcesNames Used
CTRPv2neratinib
PharmacoGx neratinib

External IDs

DatabaseIdentifier
Smiles: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
Inchikey: JWNPDZNEKVCWMY-VQHVLOKHSA-N
Pubchem: 9915743

Annotated Targets

EGFR, ERBB2, KDR

FDA Approval Status

Approved
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Top molecular features associated with response to neratinib


Feature TypeStandardized
Nominal ANOVA
mRNA ZFP62 CTRPv2 pan-cancer AAC 0.089 0.02
mRNA TMEM125 CTRPv2 pan-cancer AAC 0.096 0.02
mRNA SMAP2 CTRPv2 pan-cancer AAC -0.1 0.02
mRNA CENPI CTRPv2 pan-cancer AAC -0.088 0.02
mRNA TONSL CTRPv2 pan-cancer AAC 0.092 0.02
mRNA WWC1 CTRPv2 pan-cancer AAC 0.11 0.02
mRNA RSU1 CTRPv2 pan-cancer AAC -0.089 0.02
mRNA DEPDC1 CTRPv2 pan-cancer AAC -0.091 0.02
mRNA AL358113.1 CTRPv2 pan-cancer AAC 0.094 0.02
mRNA SOX15 CTRPv2 pan-cancer AAC 0.11 0.02
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