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neratinib

Synonyms

SourcesNames Used
CTRPv2neratinib
PharmacoGx neratinib

External IDs

DatabaseIdentifier
Smiles: CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
Inchikey: JWNPDZNEKVCWMY-VQHVLOKHSA-N
Pubchem: 9915743

Annotated Targets

EGFR, ERBB2, KDR

FDA Approval Status

Approved
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Top molecular features associated with response to neratinib


Feature TypeStandardized
Nominal ANOVA
mRNA ADCK5 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA ADGRF4 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA TINCR CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA WIPF2 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA SMIM22 CTRPv2 pan-cancer AAC 0.19 2e-06
mRNA THEM6 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA S100A16 CTRPv2 pan-cancer AAC 0.19 3e-06
mRNA SYNE4 CTRPv2 pan-cancer AAC 0.19 3e-06
mRNA GJB3 CTRPv2 pan-cancer AAC 0.2 3e-06
mRNA CKMT1B CTRPv2 pan-cancer AAC 0.18 3e-06
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