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PF-750

PF-750

Synonyms

Sources	Names Used
CTRPv2	PF-750
PharmacoGx	PF-750

External IDs

Database	Identifier
Smiles:	C1CN(CCC1CC2=CC3=CC=CC=C3N=C2)C(=O)NC4=CC=CC=C4
Inchikey:	BIODYGOZWZNCAG-UHFFFAOYSA-N
Pubchem:	25154868

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to PF-750

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FREM2	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	RNF187	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	MCM6	CTRPv2	pan-cancer	AAC	0.13	0.003
mRNA	CXADR	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	IRAK1BP1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	TSPYL1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	HNRNPU	CTRPv2	pan-cancer	AAC	0.12	0.003
mRNA	TENM1	CTRPv2	pan-cancer	AAC	0.11	0.003
mRNA	TMBIM1	CTRPv2	pan-cancer	AAC	-0.13	0.003
mRNA	SOX2	CTRPv2	pan-cancer	AAC	0.11	0.003

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