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EX-527

EX-527

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	EX-527
PharmacoGx	EX-527

External IDs

Database	Identifier
Smiles:	C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
Inchikey:	FUZYTVDVLBBXDL-UHFFFAOYSA-N
Pubchem:	5113032

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to EX-527

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SUMO4	CTRPv2	pan-cancer	AAC	0.2	2e-07
mRNA	ARHGAP40	CTRPv2	pan-cancer	AAC	0.2	2e-07
mRNA	RAPGEFL1	CTRPv2	pan-cancer	AAC	0.2	2e-07
mRNA	AL008723.1	CTRPv2	pan-cancer	AAC	0.2	3e-07
mRNA	OSM	GDSC1000	pan-cancer	AAC	0.2	3e-07
mRNA	RGR	CTRPv2	pan-cancer	AAC	0.19	3e-07
mRNA	KRT26	CTRPv2	pan-cancer	AAC	0.19	3e-07
mRNA	RP11-98L5.5	CTRPv2	pan-cancer	AAC	0.19	3e-07
mRNA	HBM	GDSC1000	pan-cancer	AAC	0.17	3e-07
mRNA	HIST1H1D	CTRPv2	pan-cancer	AAC	0.2	4e-07

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