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EX-527

EX-527

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	EX-527
PharmacoGx	EX-527

External IDs

Database	Identifier
Smiles:	C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
Inchikey:	FUZYTVDVLBBXDL-UHFFFAOYSA-N
Pubchem:	5113032

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to EX-527

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNHIT3	GDSC1000	pan-cancer	AAC	0.088	0.01
mRNA	ZNRD1	CTRPv2	pan-cancer	AAC	-0.13	0.003
mRNA	ZPBP	CTRPv2	pan-cancer	AAC	0.1	0.008
mRNA	ZPBP2	CTRPv2	pan-cancer	AAC	0.09	0.02
mRNA	ZSCAN9	GDSC1000	pan-cancer	AAC	0.088	0.009
mRNA	ZSCAN9	CTRPv2	pan-cancer	AAC	0.096	0.01
mRNA	ZWINT	GDSC1000	pan-cancer	AAC	0.083	0.02
mRNA	ZXDA	CTRPv2	pan-cancer	AAC	0.14	0.0001
mRNA	ZXDB	CTRPv2	pan-cancer	AAC	0.12	0.002
mRNA	ZYG11B	CTRPv2	pan-cancer	AAC	0.11	0.008

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