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EX-527

Synonyms

SourcesNames Used
GDSC1000, CTRPv2EX-527
PharmacoGx EX-527

External IDs

DatabaseIdentifier
Smiles: C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
Inchikey: FUZYTVDVLBBXDL-UHFFFAOYSA-N
Pubchem: 5113032

Annotated Targets

SIRT1

FDA Approval Status

Not Approved
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Top molecular features associated with response to EX-527


Feature TypeStandardized
Nominal ANOVA
mRNA OR6C1 CTRPv2 pan-cancer AAC 0.15 7e-05
mRNA RSC1A1 CTRPv2 pan-cancer AAC 0.16 7e-05
mRNA RNF150 CTRPv2 pan-cancer AAC 0.2 8e-05
mRNA ASMT CTRPv2 pan-cancer AAC 0.15 8e-05
mRNA RP11-9J18.1 CTRPv2 pan-cancer AAC 0.2 8e-05
mRNA ZMAT2 CTRPv2 pan-cancer AAC -0.15 8e-05
mRNA FASTKD1 CTRPv2 pan-cancer AAC 0.17 9e-05
mRNA CDON CTRPv2 pan-cancer AAC 0.16 9e-05
mRNA KBTBD12 CTRPv2 pan-cancer AAC 0.15 0.0001
mRNA ZNF445 CTRPv2 pan-cancer AAC 0.17 0.0001
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