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YM-155

YM-155

Synonyms

Sources	Names Used
GDSC1000	YM155
CTRPv2	YM-155
PharmacoGx	YM-155

External IDs

Database	Identifier
Smiles:	CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
Inchikey:	QBIYUDDJPRGKNJ-UHFFFAOYSA-M
Pubchem:	11178236

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to YM-155

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PPP3CB	GDSC1000	pan-cancer	AAC	0.12	0.0009
mRNA	RP11-166B2.1	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	ABCE1	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	SCNN1A	CTRPv2	pan-cancer	AAC	-0.14	0.0009
mRNA	DNAAF2	CTRPv2	pan-cancer	AAC	0.14	0.0009
mRNA	KMT5C	GDSC1000	pan-cancer	AAC	-0.11	0.0009
mRNA	PSMA8	CTRPv2	pan-cancer	AAC	0.13	0.0009
mRNA	EHD2	CTRPv2	pan-cancer	AAC	-0.14	0.0009
mRNA	MYOC	GDSC1000	pan-cancer	AAC	-0.11	0.0009
mRNA	SLC26A6	CTRPv2	pan-cancer	AAC	-0.14	0.0009

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