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YM-155

YM-155

Synonyms

Sources	Names Used
GDSC1000	YM155
CTRPv2	YM-155
PharmacoGx	YM-155

External IDs

Database	Identifier
Smiles:	CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
Inchikey:	QBIYUDDJPRGKNJ-UHFFFAOYSA-M
Pubchem:	11178236

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to YM-155

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	C11orf21	CTRPv2	pan-cancer	AAC	-0.21	6e-08
mRNA	MRPL39	CTRPv2	pan-cancer	AAC	0.21	6e-08
mRNA	RFC3	CTRPv2	pan-cancer	AAC	0.21	7e-08
mRNA	ZBTB8OS	CTRPv2	pan-cancer	AAC	0.2	7e-08
mRNA	IKZF3	CTRPv2	pan-cancer	AAC	0.23	7e-08
mRNA	CD79A	CTRPv2	pan-cancer	AAC	0.22	7e-08
mRNA	STAP1	CTRPv2	pan-cancer	AAC	0.22	8e-08
mRNA	DPEP1	GDSC1000	pan-cancer	AAC	-0.2	8e-08
mRNA	HNF4A	GDSC1000	pan-cancer	AAC	-0.2	8e-08
mRNA	ABI3	CTRPv2	pan-cancer	AAC	0.21	8e-08

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