About
Documentation
Cite Us!
Github
Download
News
Explore
Batch Query
Search
Site
Home
About
Documentation
PharmacoGx
Cite Us!
Tools
Explore
Batch Query
Search
GitHub
Datatypes
datasets
cell lines
tissues
drugs
genes
experiments
Home
/
Compounds
/
N9-isopropylolomoucine
N9-isopropylolomoucine
Synonyms
Sources
Names Used
CTRPv2
N9-isopropylolomoucine
PharmacoGx
N9-isopropylolomoucine
External IDs
Database
Identifier
Smiles:
CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCO
Inchikey:
WHDJEAZLMYPLGL-UHFFFAOYSA-N
Pubchem:
6610355
Annotated Targets
CCNB1
,
CDK1
,
CDK5
,
CDK5R1
FDA Approval Status
Not Approved
Plots
Cell Line Summary
Tissue Summary
Molecular Features
Number of cell lines tested with
N9-isopropylolomoucine (per dataset)
0
100
200
300
400
500
600
700
800
# cell lines
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
800
Download SVG
Number of tissues tested with
N9-isopropylolomoucine (per dataset)
0
2
4
6
8
10
12
14
16
18
20
22
24
# tissues
CCLE
GDSC1000
gCSI
GRAY
FIMM
UHNBreast
CTRPv2
0
0
0
0
0
0
25
Download SVG
Dataset Select
all
CTRPv2
N9-isopropylolomoucine: AAC
AAC
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0.45
0.50
CADO-ES1
CADO-ES1
NCC-StC-K140
NCC-StC-K140
CAL-78
CAL-78
SNU-1079
SNU-1079
KMS-28BM
KMS-28BM
SK-MM-2
SK-MM-2
SW1573
SW1573
SUP-M2
SUP-M2
U-2-OS
U-2-OS
HCC-1195
HCC-1195
Sq-1
Sq-1
EoL-1-cell
EoL-1-cell
NCI-H358
NCI-H358
CAL-29
CAL-29
OCI-AML3
OCI-AML3
NCI-H146
NCI-H146
Pfeiffer
Pfeiffer
NCI-H1563
NCI-H1563
ST486
ST486
KCL-22
KCL-22
MDA-MB-157
MDA-MB-157
WSU-DLCL2
WSU-DLCL2
RS4;11
RS4;11
PL-21
PL-21
SNU-81
SNU-81
YD-15
YD-15
697
697
OCI-AML2
OCI-AML2
NCI-H1734
NCI-H1734
GA-10
GA-10
COR-L95
COR-L95
BT333
BT333
SW1417
SW1417
OVISE
OVISE
Hs 688(A).T
Hs 688(A).T
Hs 839.T
Hs 839.T
NCI-H226
NCI-H226
K029AX
K029AX
Hs 822.T
Hs 822.T
Caki-2
Caki-2
IGR-39
IGR-39
A2058
A2058
A101D
A101D
KNS81
KNS81
BT328
BT328
NCI-H1184
NCI-H1184
RERF-LC-Ad1
RERF-LC-Ad1
PA-TU-8902
PA-TU-8902
OV56
OV56
A498
A498
OV-90
OV-90
SK-HEP-1
SK-HEP-1
NCI-H2196
NCI-H2196
HT-29
HT-29
JHH-6
JHH-6
BT320
BT320
BT340
BT340
BEN
BEN
MKN45
MKN45
NMC-G1
NMC-G1
CADO-ES1
NCC-StC-K140
CAL-78
SNU-1079
KMS-28BM
SK-MM-2
SW1573
SUP-M2
U-2-OS
HCC-1195
Sq-1
EoL-1-cell
NCI-H358
CAL-29
OCI-AML3
NCI-H146
Pfeiffer
NCI-H1563
ST486
KCL-22
MDA-MB-157
WSU-DLCL2
RS4;11
PL-21
SNU-81
YD-15
697
OCI-AML2
NCI-H1734
GA-10
COR-L95
BT333
SW1417
OVISE
Hs 688(A).T
Hs 839.T
NCI-H226
K029AX
Hs 822.T
Caki-2
IGR-39
A2058
A101D
KNS81
BT328
NCI-H1184
RERF-LC-Ad1
PA-TU-8902
OV56
A498
OV-90
SK-HEP-1
NCI-H2196
HT-29
JHH-6
BT320
BT340
BEN
MKN45
NMC-G1
CADO-ES1: 0.50
Synonyms: CADO-ES1, CADOES1
NCC-StC-K140: 0.46
Synonyms: NCC-StC-K140, NCCSTCK140
CAL-78: 0.35
Synonyms: CAL-78, CAL78
SNU-1079: 0.31
Synonyms: SNU-1079, SNU1079
KMS-28BM: 0.30
Synonyms: KMS-28BM, KMS28BM
SK-MM-2: 0.29
Synonyms: SK-MM-2, SKMM2
SW1573: 0.28
Synonyms: SW1573, SW 1573, SW_1573
SUP-M2: 0.28
Synonyms: SUP-M2, SUPM2
U-2-OS: 0.26
Synonyms: U-2-OS, U-2 OS, U-2_OS, U2OS
HCC-1195: 0.26
Synonyms: HCC-1195, HCC1195
Sq-1: 0.26
Synonyms: Sq-1, SQ1
EoL-1-cell: 0.25
Synonyms: EoL-1-cell, EOL-1, EOL1
NCI-H358: 0.25
Synonyms: NCI-H358, NCIH358
CAL-29: 0.25
Synonyms: CAL-29, CAL29
OCI-AML3: 0.24
Synonyms: OCI-AML3, OCIAML3
NCI-H146: 0.24
Synonyms: NCI-H146, NCIH146
Pfeiffer: 0.24
Synonyms: Pfeiffer, PFEIFFER
NCI-H1563: 0.24
Synonyms: NCI-H1563, NCIH1563
ST486: 0.24
Synonyms: ST486
KCL-22: 0.24
Synonyms: KCL-22, KCL22
MDA-MB-157: 0.24
Synonyms: MDA-MB-157, MDAMB157, mdamb157
WSU-DLCL2: 0.23
Synonyms: WSU-DLCL2, WSUDLCL2
RS4;11: 0.23
Synonyms: RS4;11, RS4_11, RS4-11, RS411
PL-21: 0.23
Synonyms: PL-21, PL21
SNU-81: 0.23
Synonyms: SNU-81, SNU81
YD-15: 0.23
Synonyms: YD-15, YD15
697: 0.23
Synonyms: 697
OCI-AML2: 0.23
Synonyms: OCI-AML2, OCIAML2
NCI-H1734: 0.23
Synonyms: NCI-H1734, NCIH1734
GA-10: 0.23
Synonyms: GA-10, GA10
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
: 0.00
Synonyms:
COR-L95: 0.03
Synonyms: COR-L95, CORL95
BT333: 0.03
Synonyms: BT333
SW1417: 0.03
Synonyms: SW1417, SW 1417
OVISE: 0.03
Synonyms: OVISE
Hs 688(A).T: 0.03
Synonyms: Hs 688(A).T, Hs_688_A_.T, HS688AT
Hs 839.T: 0.03
Synonyms: Hs 839.T, Hs_839.T, HS839T
NCI-H226: 0.03
Synonyms: NCI-H226, NCIH226
K029AX: 0.03
Synonyms: K029AX
Hs 822.T: 0.03
Synonyms: Hs 822.T, Hs_822.T, HS822T
Caki-2: 0.03
Synonyms: Caki-2, CAKI2
IGR-39: 0.03
Synonyms: IGR-39, IGR39
A2058: 0.03
Synonyms: A2058
A101D: 0.03
Synonyms: A101D
KNS81: 0.02
Synonyms: KNS81
BT328: 0.02
Synonyms: BT328
NCI-H1184: 0.02
Synonyms: NCI-H1184, NCIH1184
RERF-LC-Ad1: 0.02
Synonyms: RERF-LC-Ad1, RERFLCAD1
PA-TU-8902: 0.02
Synonyms: PA-TU-8902, PATU8902
OV56: 0.02
Synonyms: OV56, OV-56
A498: 0.02
Synonyms: A498, A-498
OV-90: 0.02
Synonyms: OV-90, OV90
SK-HEP-1: 0.02
Synonyms: SK-HEP-1, SKHEP1
NCI-H2196: 0.01
Synonyms: NCI-H2196, NCIH2196
HT-29: 0.01
Synonyms: HT-29, HT29
JHH-6: 0.01
Synonyms: JHH-6, JHH6
BT320: 0.01
Synonyms: BT320
BT340: 0.00
Synonyms: BT340
BEN: 0.00
Synonyms: BEN
MKN45: 0.00
Synonyms: MKN45, MKN-45
NMC-G1: 0.00
Synonyms: NMC-G1, NMCG1
Download SVG
0.00
0.50
1.00
1.50
2.00
2.50
3.00
3.50
4.00
4.50
5.00
5.50
SF295
SF295
SK-N-FI
SK-N-FI
HCC-1171
HCC-1171
SW1573
SW1573
FU-OV-1
FU-OV-1
HCC-15
HCC-15
IA-LM
IA-LM
SNU-410
SNU-410
SNU-626
SNU-626
SK-UT-1
SK-UT-1
MG-63
MG-63
Hs 822.T
Hs 822.T
KNS81
KNS81
NCI-H2291
NCI-H2291
A172
A172
ACC-MESO-1
ACC-MESO-1
K029AX
K029AX
LU-65
LU-65
HCC2935
HCC2935
MDA-MB-231
MDA-MB-231
BT232
BT232
Caki-2
Caki-2
BT359
BT359
HOP-92
HOP-92
KP-N-YN
KP-N-YN
KURAMOCHI
KURAMOCHI
SNU-46
SNU-46
BEN
BEN
HCC1937
HCC1937
MDA-MB-361
MDA-MB-361
GA-10
GA-10
ST486
ST486
MSTO-211H
MSTO-211H
Hs 611.T
Hs 611.T
KE-97
KE-97
NALM-6
NALM-6
NU-DHL-1
NU-DHL-1
SNU-C1
SNU-C1
NCI-H929
NCI-H929
697
697
JJN-3
JJN-3
DV-90
DV-90
OCI-AML3
OCI-AML3
YD-10B
YD-10B
EB1
EB1
WSU-DLCL2
WSU-DLCL2
EoL-1-cell
EoL-1-cell
NCI-H810
NCI-H810
A2780
A2780
NU-DUL-1
NU-DUL-1
NCC-StC-K140
NCC-StC-K140
Pfeiffer
Pfeiffer
SK-MM-2
SK-MM-2
SUP-HD1
SUP-HD1
BT239
BT239
BT16
BT16
NCI-H1299
NCI-H1299
JHUEM-2
JHUEM-2
SUP-M2
SUP-M2
SNU-1079
SNU-1079
SF295
SK-N-FI
HCC-1171
SW1573
FU-OV-1
HCC-15
IA-LM
SNU-410
SNU-626
SK-UT-1
MG-63
Hs 822.T
KNS81
NCI-H2291
A172
ACC-MESO-1
K029AX
LU-65
HCC2935
MDA-MB-231
BT232
Caki-2
BT359
HOP-92
KP-N-YN
KURAMOCHI
SNU-46
BEN
HCC1937
MDA-MB-361
GA-10
ST486
MSTO-211H
Hs 611.T
KE-97
NALM-6
NU-DHL-1
SNU-C1
NCI-H929
697
JJN-3
DV-90
OCI-AML3
YD-10B
EB1
WSU-DLCL2
EoL-1-cell
NCI-H810
A2780
NU-DUL-1
NCC-StC-K140
Pfeiffer
SK-MM-2
SUP-HD1
BT239
BT16
NCI-H1299
JHUEM-2
SUP-M2
SNU-1079
SF295: 5.89 (log10 µM)
Synonyms: SF295, SF-295
SK-N-FI: 5.39 (log10 µM)
Synonyms: SK-N-FI, SKNFI
HCC-1171: 4.83 (log10 µM)
Synonyms: HCC-1171, HCC1171
SW1573: 4.57 (log10 µM)
Synonyms: SW1573, SW 1573, SW_1573
FU-OV-1: 3.78 (log10 µM)
Synonyms: FU-OV-1, FUOV1
HCC-15: 3.76 (log10 µM)
Synonyms: HCC-15, HCC15
IA-LM: 3.68 (log10 µM)
Synonyms: IA-LM, IALM
SNU-410: 3.52 (log10 µM)
Synonyms: SNU-410, SNU410
SNU-626: 3.45 (log10 µM)
Synonyms: SNU-626, SNU626
SK-UT-1: 3.42 (log10 µM)
Synonyms: SK-UT-1, SKUT1
MG-63: 3.40 (log10 µM)
Synonyms: MG-63, MG63
Hs 822.T: 3.32 (log10 µM)
Synonyms: Hs 822.T, Hs_822.T, HS822T
KNS81: 3.30 (log10 µM)
Synonyms: KNS81
NCI-H2291: 3.25 (log10 µM)
Synonyms: NCI-H2291, NCIH2291
A172: 3.06 (log10 µM)
Synonyms: A172
ACC-MESO-1: 3.05 (log10 µM)
Synonyms: ACC-MESO-1, ACCMESO1
K029AX: 3.02 (log10 µM)
Synonyms: K029AX
LU-65: 3.00 (log10 µM)
Synonyms: LU-65, LU65
HCC2935: 3.00 (log10 µM)
Synonyms: HCC2935
MDA-MB-231: 2.99 (log10 µM)
Synonyms: MDA-MB-231, MDAMB231, mdamb231
BT232: 2.97 (log10 µM)
Synonyms: BT232
Caki-2: 2.94 (log10 µM)
Synonyms: Caki-2, CAKI2
BT359: 2.93 (log10 µM)
Synonyms: BT359
HOP-92: 2.92 (log10 µM)
Synonyms: HOP-92, HOP92
KP-N-YN: 2.91 (log10 µM)
Synonyms: KP-N-YN, KPNYN
KURAMOCHI: 2.90 (log10 µM)
Synonyms: KURAMOCHI
SNU-46: 2.87 (log10 µM)
Synonyms: SNU-46, SNU46
BEN: 2.83 (log10 µM)
Synonyms: BEN
HCC1937: 2.79 (log10 µM)
Synonyms: HCC1937, hcc1937
MDA-MB-361: 2.79 (log10 µM)
Synonyms: MDA-MB-361, MDAMB361, mdamb361
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
: 0.00 (log10 µM)
Synonyms:
GA-10: 1.52 (log10 µM)
Synonyms: GA-10, GA10
ST486: 1.52 (log10 µM)
Synonyms: ST486
MSTO-211H: 1.52 (log10 µM)
Synonyms: MSTO-211H, MSTO211H
Hs 611.T: 1.51 (log10 µM)
Synonyms: Hs 611.T, Hs_611.T, HS611T
KE-97: 1.51 (log10 µM)
Synonyms: KE-97, KE97
NALM-6: 1.51 (log10 µM)
Synonyms: NALM-6, NALM6
NU-DHL-1: 1.51 (log10 µM)
Synonyms: NU-DHL-1, NUDHL1
SNU-C1: 1.50 (log10 µM)
Synonyms: SNU-C1, SNUC1
NCI-H929: 1.50 (log10 µM)
Synonyms: NCI-H929, NCIH929
697: 1.50 (log10 µM)
Synonyms: 697
JJN-3: 1.50 (log10 µM)
Synonyms: JJN-3, JJN3
DV-90: 1.50 (log10 µM)
Synonyms: DV-90, DV90
OCI-AML3: 1.49 (log10 µM)
Synonyms: OCI-AML3, OCIAML3
YD-10B: 1.49 (log10 µM)
Synonyms: YD-10B, YD10B
EB1: 1.49 (log10 µM)
Synonyms: EB1
WSU-DLCL2: 1.49 (log10 µM)
Synonyms: WSU-DLCL2, WSUDLCL2
EoL-1-cell: 1.48 (log10 µM)
Synonyms: EoL-1-cell, EOL-1, EOL1
NCI-H810: 1.48 (log10 µM)
Synonyms: NCI-H810, NCIH810
A2780: 1.48 (log10 µM)
Synonyms: A2780
NU-DUL-1: 1.48 (log10 µM)
Synonyms: NU-DUL-1, NUDUL1
NCC-StC-K140: 1.47 (log10 µM)
Synonyms: NCC-StC-K140, NCCSTCK140
Pfeiffer: 1.46 (log10 µM)
Synonyms: Pfeiffer, PFEIFFER
SK-MM-2: 1.46 (log10 µM)
Synonyms: SK-MM-2, SKMM2
SUP-HD1: 1.44 (log10 µM)
Synonyms: SUP-HD1, SUPHD1
BT239: 1.43 (log10 µM)
Synonyms: BT239
BT16: 1.40 (log10 µM)
Synonyms: BT16
NCI-H1299: 1.39 (log10 µM)
Synonyms: NCI-H1299, NCIH1299
JHUEM-2: 1.38 (log10 µM)
Synonyms: JHUEM-2, JHUEM2
SUP-M2: 1.32 (log10 µM)
Synonyms: SUP-M2, SUPM2
SNU-1079: 1.19 (log10 µM)
Synonyms: SNU-1079, SNU1079
AAC
pIC50
* Plot represents the top and bottom 30 data points
** Error Bars represent the Median Absolute Deviation
Download SVG
Download Data as CSV
N9-isopropylolomoucine: AAC
AAC
Tissues
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0.45
0.50
cervix
cervix
kidney
kidney
pleura
pleura
central_nervous_system
central_nervous_system
unknown
unknown
liver
liver
oesophagus
oesophagus
ovary
ovary
skin
skin
biliary_tract
biliary_tract
urinary_tract
urinary_tract
thyroid
thyroid
stomach
stomach
breast
breast
lung
lung
pancreas
pancreas
prostate
prostate
endometrium
endometrium
bone
bone
large_intestine
large_intestine
soft_tissue
soft_tissue
autonomic_ganglia
autonomic_ganglia
upper_aerodigestive_tract
upper_aerodigestive_tract
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
salivary_gland
salivary_gland
-6.00
-5.00
-4.00
-3.00
-2.00
-1.00
0.00
1.00
salivary_gland
salivary_gland
haematopoietic_and_lymphoid_tissue
haematopoietic_and_lymphoid_tissue
autonomic_ganglia
autonomic_ganglia
large_intestine
large_intestine
endometrium
endometrium
soft_tissue
soft_tissue
upper_aerodigestive_tract
upper_aerodigestive_tract
bone
bone
lung
lung
stomach
stomach
thyroid
thyroid
pancreas
pancreas
biliary_tract
biliary_tract
prostate
prostate
skin
skin
unknown
unknown
breast
breast
kidney
kidney
pleura
pleura
ovary
ovary
cervix
cervix
liver
liver
oesophagus
oesophagus
urinary_tract
urinary_tract
central_nervous_system
central_nervous_system
AAC
pIC50
= Truncated outliers
Download SVG
Top molecular features associated with response to N9-isopropylolomoucine
Feature Type
Gene
Dataset
Tissue
Stat
Standardized
Coefficient
Nominal ANOVA
p-value
mRNA
CLIC4
CTRPv2
pan-cancer
AAC
-0.13
0.001
mRNA
NLRP3
CTRPv2
pan-cancer
AAC
0.12
0.001
mRNA
CR1L
CTRPv2
pan-cancer
AAC
-0.12
0.001
mRNA
NCKAP5L
CTRPv2
pan-cancer
AAC
-0.13
0.001
mRNA
C3orf58
CTRPv2
pan-cancer
AAC
0.12
0.001
mRNA
FOXP2
CTRPv2
pan-cancer
AAC
0.12
0.001
mRNA
TMTC4
CTRPv2
pan-cancer
AAC
0.12
0.001
mRNA
SH3BGRL3
CTRPv2
pan-cancer
AAC
-0.12
0.001
mRNA
TBX1
CTRPv2
pan-cancer
AAC
0.12
0.001
mRNA
NAT8L
CTRPv2
pan-cancer
AAC
0.12
0.001
← Previous
1
2
…
26
27
28
…
199
200
Next →
Download CSV