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PI-103

Synonyms

SourcesNames Used
GDSC1000, CTRPv2PI-103
PharmacoGx PI-103

External IDs

DatabaseIdentifier
Smiles: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
Inchikey: TUVCWJQQGGETHL-UHFFFAOYSA-N
Pubchem: 9884685

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PRKDC

FDA Approval Status

Not Approved
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Top molecular features associated with response to PI-103


Feature TypeStandardized
Nominal ANOVA
mRNA ADI1 GDSC1000 pan-cancer AAC -0.099 0.001
mRNA AGMAT CTRPv2 pan-cancer AAC -0.12 0.001
mRNA ZNF775 CTRPv2 pan-cancer AAC 0.12 0.001
mRNA ZNF133 GDSC1000 pan-cancer AAC 0.1 0.001
mRNA GLCE GDSC1000 pan-cancer AAC -0.11 0.001
mRNA LCP2 CTRPv2 pan-cancer AAC -0.13 0.001
mRNA EHHADH CTRPv2 pan-cancer AAC -0.12 0.001
mRNA NSRP1 GDSC1000 pan-cancer AAC 0.096 0.001
mRNA RBM39 GDSC1000 pan-cancer AAC 0.1 0.001
mRNA CYP4F11 GDSC1000 pan-cancer AAC -0.1 0.001
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