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PI-103

Synonyms

SourcesNames Used
GDSC1000, CTRPv2PI-103
PharmacoGx PI-103

External IDs

DatabaseIdentifier
Smiles: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O
Inchikey: TUVCWJQQGGETHL-UHFFFAOYSA-N
Pubchem: 9884685

Annotated Targets

MTOR, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PRKDC

FDA Approval Status

Not Approved
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Top molecular features associated with response to PI-103


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF85 GDSC1000 pan-cancer AAC 0.15 2e-06
mRNA LGALS4 CTRPv2 pan-cancer AAC -0.19 2e-06
mRNA MAU2 GDSC1000 pan-cancer AAC 0.15 2e-06
mRNA DMTF1 GDSC1000 pan-cancer AAC 0.16 2e-06
mRNA NFATC4 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA BLVRB GDSC1000 pan-cancer AAC -0.16 2e-06
mRNA AC023283.1 CTRPv2 pan-cancer AAC -0.19 2e-06
mRNA BAIAP2L2 CTRPv2 pan-cancer AAC -0.18 2e-06
mRNA TMBIM6 GDSC1000 pan-cancer AAC -0.15 2e-06
mRNA L3MBTL2 CTRPv2 pan-cancer AAC 0.17 2e-06
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