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FK866

FK866

Synonyms

Sources	Names Used
GDSC1000	FK866
CTRPv2	daporinad
PharmacoGx	FK866

External IDs

Database	Identifier
Smiles:	C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3
Inchikey:	KPBNHDGDUADAGP-VAWYXSNFSA-N
Pubchem:	6914657

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FK866

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	SYCP2L	GDSC1000	pan-cancer	AAC	0.17	6e-08
mRNA	WRN	CTRPv2	pan-cancer	AAC	0.22	6e-08
mRNA	NEUROD2	GDSC1000	pan-cancer	AAC	0.16	6e-08
mRNA	SIAH1	GDSC1000	pan-cancer	AAC	0.16	6e-08
mRNA	SDSL	GDSC1000	pan-cancer	AAC	-0.17	6e-08
mRNA	VASH2	GDSC1000	pan-cancer	AAC	0.17	6e-08
mRNA	ARHGEF25	GDSC1000	pan-cancer	AAC	0.19	6e-08
mRNA	FAM114A1	CTRPv2	pan-cancer	AAC	-0.24	6e-08
mRNA	TSKU	GDSC1000	pan-cancer	AAC	-0.19	6e-08
mRNA	ZNF428	GDSC1000	pan-cancer	AAC	0.18	6e-08

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