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FK866

FK866

Synonyms

Sources	Names Used
GDSC1000	FK866
CTRPv2	daporinad
PharmacoGx	FK866

External IDs

Database	Identifier
Smiles:	C1CN(CCC1CCCCNC(=O)C=CC2=CN=CC=C2)C(=O)C3=CC=CC=C3
Inchikey:	KPBNHDGDUADAGP-VAWYXSNFSA-N
Pubchem:	6914657

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FK866

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ARFGEF2	GDSC1000	pan-cancer	AAC	-0.19	2e-09
mRNA	TMEM74	CTRPv2	pan-cancer	AAC	0.22	3e-09
mRNA	ARHGAP19-SLIT1	CTRPv2	pan-cancer	AAC	0.26	3e-09
mRNA	FAM72D	CTRPv2	pan-cancer	AAC	0.26	3e-09
mRNA	RADIL	GDSC1000	pan-cancer	AAC	0.2	3e-09
mRNA	ELOVL2	GDSC1000	pan-cancer	AAC	0.19	3e-09
mRNA	ATP6AP2	GDSC1000	pan-cancer	AAC	-0.19	3e-09
mRNA	PPM1E	GDSC1000	pan-cancer	AAC	0.19	3e-09
mRNA	SRP9	CTRPv2	pan-cancer	AAC	0.23	3e-09
mRNA	PBRM1	CTRPv2	pan-cancer	AAC	0.25	3e-09

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