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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

FDA Approval Status

Not Approved
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA HAX1 CTRPv2 pan-cancer AAC -0.2 2e-07
mRNA PFDN2 CTRPv2 pan-cancer AAC -0.2 7e-08
mRNA SHC1 CTRPv2 pan-cancer AAC -0.2 3e-07
mRNA SEC11A CTRPv2 pan-cancer AAC -0.2 2e-08
mRNA MTX1 CTRPv2 pan-cancer AAC -0.21 1e-08
mRNA MRPL9 CTRPv2 pan-cancer AAC -0.21 1e-08
mRNA MRPL24 CTRPv2 pan-cancer AAC -0.21 4e-09
mRNA RAB13 CTRPv2 pan-cancer AAC -0.21 4e-07
mRNA DAP3 CTRPv2 pan-cancer AAC -0.23 7e-10
mRNA MCL1 CTRPv2 pan-cancer AAC -0.23 4e-11
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