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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

FDA Approval Status

Not Approved
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA YPEL1 CTRPv2 pan-cancer AAC 0.28 1e-13
mRNA SP4 CTRPv2 pan-cancer AAC 0.27 2e-13
mRNA ZNF397 CTRPv2 pan-cancer AAC 0.28 4e-13
mRNA SHISA7 CTRPv2 pan-cancer AAC 0.25 5e-13
mRNA KIAA1468 CTRPv2 pan-cancer AAC 0.26 8e-13
mRNA ZNF84 CTRPv2 pan-cancer AAC 0.27 9e-13
mRNA ZFP14 CTRPv2 pan-cancer AAC 0.26 1e-12
mRNA CRMP1 CTRPv2 pan-cancer AAC 0.29 2e-12
mRNA KCNC1 CTRPv2 pan-cancer AAC 0.28 2e-12
mRNA SUGP2 CTRPv2 pan-cancer AAC 0.3 2e-12
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