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MK 1775

MK 1775

Synonyms

Sources	Names Used
CTRPv2	MK-1775
PharmacoGx	MK 1775

External IDs

Database	Identifier
Smiles:	CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(-c2cccc(n2)C(C)(C)O)n(CC=C)c3=O)cc1
Pubchem:	24856436

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to MK 1775

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ARPP21	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	CXCL9	CTRPv2	pan-cancer	AAC	-0.12	0.0003
mRNA	DPAGT1	CTRPv2	pan-cancer	AAC	-0.12	0.0003
mRNA	RIMKLB	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	HNRNPA3	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	RNASEH2B	CTRPv2	pan-cancer	AAC	0.15	0.0003
mRNA	E2F5	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	SEPHS1	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	FOXO1	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	YY1	CTRPv2	pan-cancer	AAC	0.13	0.0003

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