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MK 1775

MK 1775

Synonyms

Sources	Names Used
CTRPv2	MK-1775
PharmacoGx	MK 1775

External IDs

Database	Identifier
Smiles:	CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n(-c2cccc(n2)C(C)(C)O)n(CC=C)c3=O)cc1
Pubchem:	24856436

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to MK 1775

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MCM5	CTRPv2	pan-cancer	AAC	0.18	4e-06
mRNA	SDC3	CTRPv2	pan-cancer	AAC	-0.21	4e-06
mRNA	YIF1A	CTRPv2	pan-cancer	AAC	-0.16	5e-06
mRNA	ESR1	CTRPv2	pan-cancer	AAC	-0.17	5e-06
mRNA	JAML	CTRPv2	pan-cancer	AAC	0.16	5e-06
mRNA	DOCK2	CTRPv2	pan-cancer	AAC	0.26	5e-06
mRNA	N4BP2	CTRPv2	pan-cancer	AAC	0.17	5e-06
mRNA	FRG1	CTRPv2	pan-cancer	AAC	0.17	5e-06
mRNA	MKI67	CTRPv2	pan-cancer	AAC	0.15	6e-06
mRNA	CCDC172	CTRPv2	pan-cancer	AAC	0.15	6e-06

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