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tivozanib

Synonyms

SourcesNames Used
GDSC1000Tivozanib
CTRPv2tivozanib
PharmacoGx tivozanib

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
Inchikey: SPMVMDHWKHCIDT-UHFFFAOYSA-N
Pubchem: 9911830

Annotated Targets

FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB, FLT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to tivozanib


Feature TypeStandardized
Nominal ANOVA
mRNA TET1 CTRPv2 pan-cancer AAC 0.21 1e-07
mRNA HMBOX1 CTRPv2 pan-cancer AAC 0.25 1e-07
mRNA C17orf99 CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA DCUN1D4 GDSC1000 pan-cancer AAC 0.18 1e-07
mRNA R3HDM4 CTRPv2 pan-cancer AAC 0.2 1e-07
mRNA GOLGA8T CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA MS4A4E CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA HHEX CTRPv2 pan-cancer AAC 0.2 2e-07
mRNA LTB4R2 GDSC1000 pan-cancer AAC 0.18 2e-07
mRNA KIAA1586 CTRPv2 pan-cancer AAC 0.2 2e-07
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