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tivozanib

Synonyms

SourcesNames Used
GDSC1000Tivozanib
CTRPv2tivozanib
PharmacoGx tivozanib

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
Inchikey: SPMVMDHWKHCIDT-UHFFFAOYSA-N
Pubchem: 9911830

Annotated Targets

FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB, FLT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to tivozanib


Feature TypeStandardized
Nominal ANOVA
mRNA YPEL4 CTRPv2 pan-cancer AAC 0.19 6e-08
mRNA AHSP CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA GFI1B CTRPv2 pan-cancer AAC 0.19 7e-08
mRNA LEPR CTRPv2 pan-cancer AAC 0.19 8e-08
mRNA HBE1 CTRPv2 pan-cancer AAC 0.19 8e-08
mRNA RP11-864I4.1 CTRPv2 pan-cancer AAC 0.22 9e-08
mRNA C1QTNF4 CTRPv2 pan-cancer AAC 0.19 9e-08
mRNA TIFAB CTRPv2 pan-cancer AAC 0.19 9e-08
mRNA ZNF627 GDSC1000 pan-cancer AAC 0.19 9e-08
mRNA GMFG CTRPv2 pan-cancer AAC 0.27 1e-07
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