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tivozanib

Synonyms

SourcesNames Used
GDSC1000Tivozanib
CTRPv2tivozanib
PharmacoGx tivozanib

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
Inchikey: SPMVMDHWKHCIDT-UHFFFAOYSA-N
Pubchem: 9911830

Annotated Targets

FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB, FLT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to tivozanib


Feature TypeStandardized
Nominal ANOVA
mRNA RASGRP1 GDSC1000 pan-cancer AAC -0.1 0.007
mRNA CD5L CTRPv2 pan-cancer AAC -0.098 0.007
mRNA LSM1 CTRPv2 pan-cancer AAC 0.098 0.007
mRNA SYNE1 GDSC1000 pan-cancer AAC -0.1 0.007
mRNA DDAH2 CTRPv2 pan-cancer AAC 0.11 0.007
mRNA ARHGEF35 CTRPv2 pan-cancer AAC -0.12 0.007
mRNA TBCEL CTRPv2 pan-cancer AAC -0.1 0.007
mRNA TBCA GDSC1000 pan-cancer AAC 0.095 0.007
mRNA VAC14 CTRPv2 pan-cancer AAC -0.098 0.007
mRNA MEIOB CTRPv2 pan-cancer AAC 0.1 0.007
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