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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA OR2B11 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA RP11-111H13.1 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA PPIC CTRPv2 pan-cancer AAC -0.16 0.0002
mRNA SPARC CTRPv2 pan-cancer AAC -0.16 0.0002
mRNA POLE2 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA RFT1 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA SLC8A1 CTRPv2 pan-cancer AAC -0.14 0.0003
mRNA PGAM5 CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA NUP50 CTRPv2 pan-cancer AAC 0.14 0.0003
mRNA ZBED4 CTRPv2 pan-cancer AAC 0.16 0.0003
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