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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA SLC12A8 CTRPv2 pan-cancer AAC -0.081 0.03
mRNA MASP2 CTRPv2 pan-cancer AAC 0.079 0.03
mRNA MESP1 CTRPv2 pan-cancer AAC -0.084 0.03
mRNA ECSCR CTRPv2 pan-cancer AAC 0.078 0.03
mRNA IL26 CTRPv2 pan-cancer AAC 0.078 0.03
mRNA SNRPB CTRPv2 pan-cancer AAC 0.079 0.03
mRNA PTPN11 CTRPv2 pan-cancer AAC 0.08 0.03
mRNA HACE1 CTRPv2 pan-cancer AAC 0.08 0.03
mRNA SHROOM4 CTRPv2 pan-cancer AAC -0.088 0.03
mRNA CD300C CTRPv2 pan-cancer AAC 0.081 0.03
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