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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA RABGGTB CTRPv2 pan-cancer AAC 0.14 8e-05
mRNA GRAMD3 CTRPv2 pan-cancer AAC -0.16 9e-05
mRNA CHPF CTRPv2 pan-cancer AAC -0.16 9e-05
mRNA PELP1 CTRPv2 pan-cancer AAC 0.15 9e-05
mRNA ZNF699 CTRPv2 pan-cancer AAC 0.14 9e-05
mRNA PML CTRPv2 pan-cancer AAC -0.16 9e-05
mRNA PCDHGA11 CTRPv2 pan-cancer AAC -0.18 9e-05
mRNA ZNF100 CTRPv2 pan-cancer AAC 0.15 9e-05
mRNA MAP3K15 CTRPv2 pan-cancer AAC 0.14 9e-05
mRNA KRI1 CTRPv2 pan-cancer AAC 0.17 0.0001
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