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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA VCAM1 CTRPv2 pan-cancer AAC -0.082 0.03
mRNA CCDC50 CTRPv2 pan-cancer AAC -0.08 0.03
mRNA KLF5 CTRPv2 pan-cancer AAC -0.1 0.03
mRNA TMEM161B CTRPv2 pan-cancer AAC 0.081 0.03
mRNA MYD88 CTRPv2 pan-cancer AAC -0.086 0.03
mRNA DDR1 CTRPv2 pan-cancer AAC -0.098 0.03
mRNA PRRX2 CTRPv2 pan-cancer AAC -0.084 0.03
mRNA ZNF622 CTRPv2 pan-cancer AAC -0.081 0.03
mRNA JOSD2 CTRPv2 pan-cancer AAC -0.086 0.03
mRNA METTL21A CTRPv2 pan-cancer AAC 0.087 0.03
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