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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA PRIM1 CTRPv2 pan-cancer AAC 0.21 5e-08
mRNA MAPK8 CTRPv2 pan-cancer AAC 0.2 6e-08
mRNA ZNF583 CTRPv2 pan-cancer AAC 0.19 9e-08
mRNA ZNF679 CTRPv2 pan-cancer AAC 0.18 2e-07
mRNA ZNF714 CTRPv2 pan-cancer AAC 0.18 6e-07
mRNA ARHGAP19 CTRPv2 pan-cancer AAC 0.22 1e-06
mRNA ARHGAP19-SLIT1 CTRPv2 pan-cancer AAC 0.21 1e-06
mRNA MIS18A CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA PHGDH CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA RP11-894J14.5 CTRPv2 pan-cancer AAC 0.19 2e-06
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