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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA BCL6B CTRPv2 pan-cancer AAC 0.1 0.004
mRNA SERPINB7 CTRPv2 pan-cancer AAC -0.11 0.004
mRNA NUDT13 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA DSTN CTRPv2 pan-cancer AAC -0.12 0.004
mRNA SNAI3 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA LRP1 CTRPv2 pan-cancer AAC -0.12 0.004
mRNA CSTF2 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA ZNF345 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA USB1 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA CD79A CTRPv2 pan-cancer AAC -0.11 0.004
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