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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA PCDHGC5 CTRPv2 pan-cancer AAC -0.18 6e-05
mRNA AK2 CTRPv2 pan-cancer AAC 0.15 6e-05
mRNA CCDC3 CTRPv2 pan-cancer AAC 0.15 6e-05
mRNA PCDHGB1 CTRPv2 pan-cancer AAC -0.18 6e-05
mRNA MYO18B CTRPv2 pan-cancer AAC 0.15 6e-05
mRNA VASN CTRPv2 pan-cancer AAC -0.16 7e-05
mRNA NDC1 CTRPv2 pan-cancer AAC 0.15 7e-05
mRNA KIF2C CTRPv2 pan-cancer AAC 0.15 7e-05
mRNA ABCB7 CTRPv2 pan-cancer AAC 0.16 7e-05
mRNA PCDHGA10 CTRPv2 pan-cancer AAC -0.18 8e-05
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